Characteristics of tremor in Parkinson disease， essential tremor， and neuronal intranuclear inclusion disease
10.19845/j.cnki.zfysjjbzz.2025.0020
- VernacularTitle:帕金森病、原发性震颤和神经元核内包涵体病的震颤特点
- Author:
Huanhuan FENG
1
;
Erhe XU
1
Author Information
1. Department of Neurology， Xuanwu Hospital， Capital Medical University， Beijing 100053， China
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
Essential tremor;
Neuronal intranuclear inclusion disease;
Tremor
- MeSH:
Parkinson Disease;
Tremor
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(2):99-103
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of tremor in Parkinson disease （PD）， essential tremor （ET）， and neuronal intranuclear inclusion disease （NIID）. Methods The surface electromyography （sEMG） data of both upper limbs were collected from 73 patients with tremor （30 patients in PD group， 23 in ET group， and 20 in NIID group）， and the a power spectral analysis was used to investigate frequency characteristics. A one-way analysis of variance and the chi-square test were used for comparison of electrophysiological parameters on sEMG between the three groups. Results The ET group had a higher tremor frequency than the PD group （F=41.86， P<0.01）， while the PD group had a higher tremor frequency than the NIID group in resting state （F=41.86， P=0.002） and in postural state （F=41.86， P=0.011）. The PD group had a higher proportion of patients with alternating contractions than the NIID group in resting state （χ2=5.70， P=0.017） and in postural state （χ2=7.24， P=0.007）， as well as a higher proportion of such patients than the ET group （χ2=9.67， P=0.002）. The PD group also had a higher proportion of patients with harmonic resonances than the NIID group in resting state （χ2=4.64， P=0.031） and in postural state （χ2=7.73， P=0.005）， as well as a higher proportion of such patients than the ET group （χ2=6.52， P=0.011）. Conclusion The highest tremor frequency is observed in ET， while the lowest tremor frequency is observed in NIID； patients with PD have a higher proportion of individuals with alternating contractions or harmonic resonances than patients with NIID and ET.
- Full text:2025071513292478073帕金森病、原发性震颤和神经元核内包涵体病的震颤特点.pdf
