Current status of epilepsy treatment and efficacy of phenobarbital in rural areas of Heilongjiang Province, China
10.19845/j.cnki.zfysjjbzz.2025.0011
- VernacularTitle:黑龙江省农村地区癫痫治疗现状以及苯巴比妥疗效分析
- Author:
Weili HE
1
;
Shichun YAN
1
Author Information
1. Division of Chronic Disease Control and Prevention, Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150030, China
- Publication Type:Journal Article
- Keywords:
Rural areas;
Epilepsy;
Current status of treatment;
Phenobarbital
- MeSH:
Phenobarbital
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(1):52-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the current status of treatment for patients with convulsive epilepsy in rural areas of Heilongjiang Province, China and the efficacy of phenobarbital in the treatment of epilepsy, and to evaluate the effect of the epilepsy prevention and management project in rural areas. Methods EpiData, EXCEL, and SPSS 19.0 were used for data entry, processing, and statistical description to analyze the current status of epilepsy treatment in rural areas, the dose of phenobarbital, and the frequency of seizures. In the epilepsy prevention and management project of Heilongjiang Province in 2015—2020, a total of 908 patients with convulsive epilepsy were enrolled in the phenobarbital treatment group, and after standardized treatment and follow-up management, 698 patients were followed up for at least 12 months. Results The gap rate of rural epilepsy treatment in Heilongjiang Province was 56.39%. After one year of standardized treatment, the frequency of seizures decreased from 23.86 times/year before enrollment to 3.11 times/year, showing a significant reduction. The response rate of epilepsy treatment was 68.19%, and the patients without previous standard treatment tended to have a better outcome than those who received standard treatment. Conclusion The current status of epilepsy treatment is not optimistic in rural areas of Heilongjiang Province, and there remains a large gap in epilepsy treatment. It is necessary to strengthen the training on the diagnosis and treatment of epilepsy among primary care physicians and implement the public education on the prevention and treatment of epilepsy, and since phenobarbital has a marked clinical effect in the treatment of epilepsy, it holds promise for further application in rural areas.
- Full text:2025071510240923094黑龙江省农村地区癫痫治疗现状以及苯巴比妥疗效分析.pdf