Association between the pattern of carotid artery calcification and the short-term prognosis of patients with acute cerebral infarction
10.19845/j.cnki.zfysjjbzz.2025.0008
- VernacularTitle:颈动脉钙化模式与急性脑梗死患者短期预后的相关研究
- Author:
Jianwei WANG
1
;
Yaming FU
1
Author Information
1. Department of Neurology，Affiliated Jinhua Hospital，Zhejiang University School of Medicine，Jinhua 321000，China
- Publication Type:Journal Article
- Keywords:
Acute cerebral infarction;
Carotid artery calcification;
Prognosis;
Hemorrhagic transformation;
Intimal calcification
- MeSH:
Prognosis
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(1):38-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between the pattern of carotid artery calcification and the prognosis of patients with acute cerebral infarction after 3 months of treatment. Methods A total of 112 patients who were diagnosed with acute ischemic stroke （AIS） in our hospital from March 2021 to September 2022 were enrolled as subjects. CT angiography was performed within 24 hours after admission， and the carotid artery was assessed in terms of calcification pattern （no calcification， intimal calcification， and medial calcification） and calcification load （low and high calcification）. After 7 days of treatment， CT reexamination was performed to evaluate hemorrhagic transformation and infarct volume. The patients were followed up for 3 months， and according to the modified Rankin Scale （mRS） score， they were divided into good prognosis group （82 patients with an mRS score of <3 points） and poor prognosis group （30 patients with an mRS score of ≥3 points）. Results Compared with the good prognosis group， the poor prognosis group had a significantly higher proportion of patients with an age of ≥70 years， a mean systolic blood pressure of ≥165 mmHg， a fasting blood glucose level of ≥7.5 mmol/L， an NIHSS score of ≥12 on admission， intimal calcification， medial calcification， high calcification， hemorrhagic transformation， and an infarct volume of ≥50 mm3 （P<0.05）. The multivariate logistic regression analysis showed that NIHSS score ≥12 on admission， intimal calcification， hemorrhagic transformation， and infarct volume ≥50 mm3 were risk factors for poor prognosis （P<0.05）. Conclusion Intimal calcification of the carotid artery may be associated with the poor short-term prognosis of AIS patients， which can be used as a new noninvasive indicator for predicting prognosis.
- Full text:2025071509572557843颈动脉钙化模式与急性脑梗死患者短期预后的相关研究.pdf
