Research progress on natural products regulating osteogenic differentiation

VernacularTitle:天然产物调控成骨分化的研究进展
Author: Hu CAI ^{1
,

2
,

3} ; Xiaoqian WU ; Lingfei HAN ; Feng FENG ; Wei QU ; Wenyuan LIU
Author Information

1. 中国药科大学药物分析系, 南京 211198
2. 中国药科大学中药学院, 南京 211198
3. 浙江省原料药安全研究中心, 杭州 310018
Publication Type:Journal Article
Keywords: natural products; osteogenic differentiation; research progress
From: Journal of China Pharmaceutical University 2025;56(1):10-21
CountryChina
Language:Chinese
Abstract: As the important source of bone cells, osteoblasts are involved in bone formation and repair, and play a key role in maintaining bone balance. If the osteogenic differentiation process in vivo is disrupted, a variety of bone-related diseases may occur. Natural products, which have a wide range of sources, a wide variety of physiological activities, and few toxic side-effects, have been found in recent years to be able to regulate osteoblast differentiation. Based on the sources of natural products, this paper reviews the intervention of natural products from plant, animal and microbial sources on osteogenic differentiation, aiming to provide a theoretical basis for natural products in the treatment of bone diseases.