Effect of Huoxin pill (concentrated pill) combined with Baduanjin on prognosis after interventional operation of acute myocardial infarction complicated with heart failure
10.12206/j.issn.2097-2024.202308034
- VernacularTitle:活心丸（浓缩丸）联合八段锦对急性心肌梗死合并心力衰竭介入术预后的影响
- Author:
Peng WANG
1
;
Zhengyan ZHANG
2
;
Zonggui WU
3
Author Information
1. Department of Pharmacy, b. Department of Cardiology, c. Department of Rehabilitation, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China.
2. b. Department of Cardiology,.
3. b. Department of Cardiology, c. Department of Rehabilitation, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China.
- Publication Type:Medicine&Clinical
- Keywords:
acute myocardial infarction;
heart failure;
percutaneous coronary intervention;
comprehensive therapy of traditional chinese medicine
- From:
Journal of Pharmaceutical Practice and Service
2025;43(7):348-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Huoxin pill （concentrated pill） combined with Baduanjin on the prognosis of patients with acute myocardial infarction complicated by percutaneous coronary intervention （PCI）. Methods 120 patients with acute myocardial infarction complicated with heart failure who received emergency interventional treatment in our hospital from January 2022 to January 2023 were randomly divided into western medicine treatment group and Traditional Chinese Medicine （TCM）comprehensive treatment group. Western medicine treatment: standard western medicine treatment + five prescriptions for cardiac rehabilitation; based on western medicine treatment, Huoxin pill （concentrated pill） combined with Baduanjin therapy was added to the TCM comprehensive treatment group, and the follow-up was 6 months. The observed indexes were exertion angina pectoris scale, Chinese Medicine Syndrome Scale, Chinese medicine syndrome treatment effect evaluation, 6-minute walking test （6MWT）, left ventricular ejection fraction （LVEF）, and brain natriuretic peptide precursor （pro-BNP）. Results Sixty patients were enrolled in the two groups respectively. During the treatment, 2 cases fell off in the western medicine treatment group and 8 cases fell off in the TCM comprehensive treatment group, and a total of 110 cases were enrolled in the group. Compared with the western treatment group, TCM combined therapy significantly improved angina pectoris scale score, TCM Syndrome Scale score, pro-BNP, LVEF and 6MWT （P<0.001）. There were no significant differences in blood routine, liver and kidney function, potassium, blood glucose, blood lipids and cardiac Troponin I （cTnI） between the two groups （P>0.05）. No adverse cardiovascular events occurred during the entire treatment period in both groups. Conclusion Huoxin pill （concentrated pill） combined with Baduanjin was more effective than western therapy in improving LVEF, 6MWT distance, exercise tolerance and cardiac function in patients with acute myocardial infarction complicated with heart failure.
