Treatment of Coexisting Dryness and Dampness in Sjögren's Syndrome Based on "Three Methods for Liver Diseases"
10.13288/j.11-2166/r.2025.14.014
- VernacularTitle:从“肝病三法”论治燥湿互结型干燥综合征
- Author:
Yuze LIU
1
;
Fengtao PANG
2
;
Jiale HE
2
;
Xiaopo TANG
2
Author Information
1. Beijing University of Chinese Medicine,Beijing,100029
2. Guang'anmen Hospital,China Academy of Chinese Medical Sciences
- Publication Type:Journal Article
- Keywords:
Sjögren's syndrome;
coexisting dryness and dampness;
three methods for liver diseases;
Guide to Clinical Case (《临证指南医案》)
- From:
Journal of Traditional Chinese Medicine
2025;66(14):1495-1498
- CountryChina
- Language:Chinese
-
Abstract:
This paper summarizes clinical insights on treating the syndrome of coexisting dryness and dampness in Sjögren's syndrome (SS) based on the "three methods for liver diseases". It is proposed that the core pathogenesis of this subtype lies in the liver's failure to regulate and disperse, leading to fluid retention and transformation into dryness; disharmony between wood (liver) and earth (spleen), resulting in internal generation of dryness and dampness; and liver impairment affecting the kidney, eventually causing extreme dryness to transform into dampness. This syndrome is thus characterized by disharmony between the liver and spleen, as well as dysfunction between ti (character, 体) and yong (function, 用). Drawing from the Guide to Clinical Case (《临证指南医案》), the "three methods for liver diseases" are applied as follows,i.e. using pungent and dispersing herbs to regulate the liver and resolve qi stagnation; using sweet and gentle herbs to soothe the liver and address the root of concurrent dryness and dampness; and using sour and purgative herbs to soften the liver and restore fluid balance. The coordinated use of these three methods, treating both ti and yong, facilitates the separation of dryness and dampness, providing a novel approach to syndrome differentiation and treatment for this subtype of SS.