Radiation protection monitoring and recommendations for yttrium-90 microsphere selective internal radiotherapy
10.20001/j.issn.2095-2619.20250413
- VernacularTitle:钇-90微球选择性内放射治疗放射防护检测与防护措施建议
- Author:
Xiangyong FAN
1
;
Wei CHEN
;
Xingjiang CAO
;
Yuji MIAO
;
Xiaosan XU
;
Jin WANG
Author Information
1. Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu 210009, China
- Publication Type:Journal Article
- Keywords:
Yttrium-90 microsphere;
Selective internal radiotherapy;
Radiation dose;
Radiation protection;
Hepatocellular carcinoma;
Radiation workers;
Nuclear medicine;
Interventional radiology
- From:
China Occupational Medicine
2025;52(2):193-197
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the external radiation dose rate and radiation protection measures during treatment of a patient with hepatocellular carcinoma (HCC) who underwent 90Y selective internal radiotherapy (⁹⁰Y-SIRT). Methods A male HCC patient who received ⁹⁰Y-SIRT with an activity of 4.65×10⁹ Bq was selected as the research subject using retrospective analysis. External radiation dose rate meters were used to detect ambient dose equivalent rates around the radiation worker, the HCC patient, and the workplace during treatment. Surface contamination meters were used to detect surface contamination levels of the radiation worker and the workplace. Results The ambient dose equivalent rate around the interventional radiology staff during treatment ranged from 3.7 to 39.0 μSv/h. The patient's ambient dose equivalent rate of surgical site at distances of 30, 100, and 200 cm ranged from 45.0 to 5.6, 4.4 to 0.4, and 0.4 to 0.1 μSv/h respectively without protection, and 14.0 to 3.4, 3.2 to 0.3, and 0.4 to 0.1 μSv/h respectively when the surgical site was covered with a 1.0 mmPb lead rubber drape after 0.0 to 161.0 hours of the surgery. In the nuclear medicine department, ambient dose equivalent rate of the workplace ranged from 0.4 to 740.0 μSv/h. The ambient dose equivalent rate around all monitoring points in the digital subtraction angiography operating room accounted at 0.1 μSv/h, and the observation ward ranged from 0.1 to 0.2 μSv/h. The β surface contamination levels of the radiation worker and workplace were below the minimum detection limit (0.16 Bq/cm²). Conclusion Radiation doses for both HCC patients and radiation worker remained within acceptable limits when appropriate protective equipment was used. A well-designed workplace layout is essential to ensure effective implementation of radiation protection.
