Simultaneous determination of four thiol derivatives in workplace air by gas chromatography
10.20001/j.issn.2095-2619.20250412
- VernacularTitle:气相色谱法同时测定工作场所空气中4种硫醇类化合物
- Author:
Ruibo MENG
1
;
Jing YUAN
;
Jiawen HU
;
Jiaheng HE
;
Jingjing QIU
;
Zuokan LIN
;
Ziqun ZHANG
;
Weifeng RONG
;
Banghua WU
Author Information
1. Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, Guangdong 510300, China
- Publication Type:Journal Article
- Keywords:
Workplace;
Air;
Thiol derivatives;
Air sampling tube;
Gas chromatography method
- From:
China Occupational Medicine
2025;52(2):188-192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for simultaneous determination of four high-molecular-weight thiol derivatives (TDs) in workplace air by gas chromatography. Methods The four kinds of vapor-phase macromolecular TDs (1-pentanethiol, 1-hexanethiol, 1-benzyl mercaptan, and n-octanethiol) in the workplace air were collected using the GDH-1 air sampling tubes, desorbed with anhydrous ethanol, separated on a DB-FFAP capillary column, and determined by flame ionization detector. Results The quantitation range of the four TDs was 0.30-207.37 mg/L, with the correlation coefficients greater than 0.999 00. The minimum detection mass concentrations and minimum quantitation mass concentrations were 0.18-0.32 and 0.60-1.05 mg/m3, respectively (both calculated based on the 1.5 L sample and 3.0 mL desorption solvent). The mean desorption efficiencies ranged from 87.07% to 103.59%. The within-run and between-run relative standard deviations were 1.92%-8.22% and 1.89%-8.45%, respectively. The samples can be stored at room temperature or 4 ℃ for three days and up to 7 days at -18 ℃. Conclusion This method is suitable for the simultaneous determination of four vapor-phase TDs in workplace air.
