Modern Clinical Application and Mechanism of Action of Chaihu Guizhi Ganjiangtang： A Review
10.13422/j.cnki.syfjx.20250894
- VernacularTitle:柴胡桂枝干姜汤现代临床应用及作用机制研究进展
- Author:
Miaomiao MENG
1
;
Zibo YUAN
1
;
Kaili CHEN
1
;
Jun ZHANG
2
;
Zixuan YU
1
;
Wei DENG
3
Author Information
1. The First School of Clinical Medicine，Henan University of Chinese Medicine，Zhengzhou 450003，China
2. The First Affiliated Hospital of Zhengzhou University，Zhengzhou 450052，China
3. The First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450003，China
- Publication Type:Journal Article
- Keywords:
Chaihu Guizhi Ganjiangtang;
famous classical formulas;
clinical application;
mechanism of action
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(16):266-277
- CountryChina
- Language:Chinese
-
Abstract:
Chaihu Guizhi Ganjiangtang （CGG）is a classic prescription in the Treatise on Cold Damage，which has the effects of clearing and relieving stagnation heat in Shaoyang，warming and dissolving water drink，and relieving the pivot mechanism. It is a classic prescription for treating spleen deficiency and liver depression and stopping internal stagnation caused by water drink. The formula is exquisite and well-matched and is often modified and used by ancient and modern medical practitioners to treat various miscellaneous diseases of internal and external medicine，with significant therapeutic effects. In recent years，with the rapid development of modern pharmacology，research on the micro mechanism of CGG has been continuously developed and deepened，providing new ideas for the treatment of diseases with CGG. Therefore，the authors systematically searched databases such as China National Knowledge Infrastructure，Wanfang Data Knowledge Service Platform，VIP Database， and PubMed for literature on the clinical application and pharmacological mechanism of CGG published by Chinese and foreign scholars in recent years. This article summarized the literature from two aspects：the modern clinical application and mechanism of action of CGG and elaborated on the diseases treated by CGG in modern literature，involving digestive system，respiratory system，nervous system，endocrine system，circulatory system，urinary system，gynecology，as well as its application in reducing the side effects of radiotherapy and chemotherapy， gynecology， dermatology， ophthalmology， and orthopedics. At the same time，the mechanism of CGG in treating diseases may be related to anti-inflammatory，anti-oxidative stress， regulation of immunity， anti-fibrosis， anti-tumor， improvement of gastrointestinal flora and motility， protection of liver tissue， reduction of blood lipids and blood sugar， and regulation of hormone levels.
