Efficacy of praziquantel (Cesocide injection) in treatment of cestode infections in domestic and laboratory animals.
10.3347/kjp.1988.26.2.121
- Author:
Kee Seon EOM
1
;
Seung Ho KIM
;
Han Jong RIM
Author Information
1. Department of Parasitology,College of Medicine, Chungbuk National University, Cheonju 360-763, Korea.
- Publication Type:Original Article
- MeSH:
parasitology-helminth-cestoda;
Dipylidium caninum;
Spirometra sp.;
Taenia pisiformis;
Taenia taeniaeformis;
Hymenolepis nana;
Moniezia expansa;
Moniezia sp.;
Raillietina sp.;
dog;
cat;
rat;
mouse;
goat;
deer;
chicken;
chemotherapy;
praziquantel;
intramuscular injection;
animals;
tapeworms;
cestodes
- From:The Korean Journal of Parasitology
1988;26(2):121-126
- CountryRepublic of Korea
- Language:English
-
Abstract:
Efficacy of praziquantel (Cesocide injection) by intramuscular (I.M.) route against cestode infections was evaluated. Total 93 domestic or laboratory animals such as dogs, cats, rats, mice, goats, deers and chickens were used. Animals were infected with Dipylidium caninum, Spirometra sp., Taenia pisiformis, Taenia taeniaeformis, Hymenolepis nana, Moniezia expansa, Moniezia sp. or Raillietina sp. A single dose of praziquantel, 6 mg/kg of body weight, was highly effective (97.9%) against cestodes of various kinds disregarding the host species or their intensity of infection. At high dose above 6 mg/kg, the cure rate was 100%. All the cestodes treated were expelled from the host within 48 hours. The discharged proglottids were damaged severely except Hymenolepis nana and Moniezia expansa. Intramuscular injection of this drug evoked a brief pain response in a dog, but no other side reactions were observed.
