Comparison of detection and manifestations of metastatic hepatocellular carcinoma by ultrasound at different frequencies
10.12025/j.issn.1008-6358.2025.20241181
- VernacularTitle:不同频率超声检出转移性肝癌及表现比较
- Author:
Hong QIN
1
;
Yuli ZHU
1
;
Qiannan ZHAO
1
;
Feihang WANG
2
;
Hansheng XIA
1
;
Wentao KONG
3
;
Wenping WANG
2
,
4
Author Information
1. Department of Ultrasound, Zhongshan Hospital, Fudan university, Shanghai 200032, China.
2. Shanghai Institute of Imaging Medicine, Shanghai 200032, China.
3. Department of Ultrasonic Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing 210003, Jiangsu, China.
4. Department of Ultrasound, Zhongshan Hospital, Fudan university, Shanghai 200032, China
- Publication Type:Techniqueandmethod
- Keywords:
contrast-enhanced ultrasound;
superficial metastatic hepatocellular carcinoma;
high-frequency ultrasound;
low-frequency ultrasound
- From:
Chinese Journal of Clinical Medicine
2025;32(3):500-504
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of high-frequency ultrasound in the detection of metastatic hepatocellular carcinoma and displaying lesion characteristics. Methods A total of 38 paitients with hepatocellular carcinoma satellite lesions within 40 mm of subcutaneous tissue were underwent low-frequency (1-5 MHz) and high-frequency (6-9 MHz) ultrasound. Detection rates and ultrasonic features were compared. Results High-frequency grayscale ultrasound had a higher detection rate (71.1% vs. 36.8%, P＜0.001). Subgroup analysis showed higher detection rates with chemotherapy history (88.9% vs. 33.3%, P＝0.002), fatty liver (71.9% vs 31.3%, P＜0.001) or superficial lesion (within 20 mm, 76.5% vs 41.2%, P＝0.031). High-frequency ultrasound also showed clearer margins (P＝0.004) and more arterial-phase rim enhancement (P＝0.007). Conclusions 6-9 MHz ultrasound detects metastatic hepatocellular carcinoma, especially superficial lesions, more effectively than 1-5 MHz ultrasound and better visualizes characteristics.
