New advances in perioperative fluid management in lung transplantation
10.12464/j.issn.1674-7445.2025080
- VernacularTitle:肺移植围手术期液体管理的新进展
- Author:
Meng SUI
1
;
Murong HUANG
1
;
Ranming MA
1
;
Mochi WANG
1
;
Chunxiao HU
1
Author Information
1. Department of Anesthesiology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214023, China.
- Publication Type:ReviewArticle
- Keywords:
Lung transplantation;
Fluid management;
Pulmonary edema;
Primary graft dysfunction;
Acute kidney injury;
Liberal fluid administration;
Restrictive fluid administration;
Goal-directed fluid therapy
- From:
Organ Transplantation
2025;16(4):648-652
- CountryChina
- Language:Chinese
-
Abstract:
Lung transplantation is an effective treatment for various end-stage lung diseases. Optimizing perioperative fluid management can reduce the incidence of postoperative pulmonary edema and improve the prognosis of lung transplant recipients. Excessive fluid administration may lead to pulmonary edema, ischemia-reperfusion injury of the transplant lung, and increased cardiac burden, which can induce heart failure. On the other hand, overly strict fluid restriction may lead to hypovolemia, affecting tissue perfusion and causing organ dysfunction. Therefore, precise regulation of fluid balance is crucial for the postoperative recovery of lung transplant recipients. This article reviews the physiological characteristics of lung transplant recipients, types of infused fluids, fluid therapy regimens, and hemodynamic monitoring, aiming to elucidate the particularities of perioperative fluid management in lung transplantation and provide new ideas and directions for individualized fluid management.
