Influencing factors, clinical manifestations and preventive strategies of hypercoagulable state after kidney transplantation
10.12464/j.issn.1674-7445.2025055
- VernacularTitle:肾移植术后血液高凝状态的影响因素、临床表现与预防策略
- Author:
Rentian CHEN
1
;
Zehua YUAN
1
;
Hongtao JIANG
1
;
Tao LI
1
;
Meng YANG
1
;
Liang XU
1
;
Yi WANG
1
Author Information
1. Department of Kidney Transplantation, the Second Affiliated Hospital of Hainan Medical University, Haikou 570100, China.
- Publication Type:ReviewArticle
- Keywords:
Kidney transplantation;
Hypercoagulable state;
Thrombosis;
Immunosuppressant;
Coagulation factor;
Platelet;
Rejection;
Vascular complication
- From:
Organ Transplantation
2025;16(4):640-647
- CountryChina
- Language:Chinese
-
Abstract:
Hypercoagulable state (HCS) after kidney transplantation is one of the common and serious complications in kidney transplant recipients, which has attracted increasing attention in recent years. HCS refers to the abnormal and excessive activation of blood coagulation function, leading to the increased risk of thrombosis. After kidney transplantation, the combined effects of hemodynamic changes, surgical trauma and severe rejection increase the incidence of HCS, not only raising the risk of thrombosis but also potentially causing graft failure and affecting the postoperative survival rate of patients. This article reviews the influencing factors, clinical manifestations, diagnostic methods and preventive strategies of HCS after kidney transplantation, aiming to provide a theoretical basis for optimizing perioperative management and improving the prognosis of patients.
