Research advances on the role of peripheral immunity in the development and progression of Alzheimer disease
10.19845/j.cnki.zfysjjbzz.2024.0220
- VernacularTitle:外周免疫在阿尔茨海默病发生发展中作用的研究进展
- Author:
Can CUI
1
;
Xinyu ZHAO
1
Author Information
1. The First Affiliated Hospital of Zhengzhou University， Zhengzhou 450000， China
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Peripheral immunity;
Pathogenesis
- MeSH:
Alzheimer Disease
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(12):1148-1152
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer disease（AD）， a degenerative disease of the central nervous system characterized by progressive cognitive dysfunction and behavioral impairment， has gradually become one of the most burdensome diseases in this century. At present， the amyloid cascade hypothesis is a widely recognized theory on the pathogenesis of AD. However， recent studies have shown that the immune system can play an important role in the occurrence of AD. This article summarizes the relationship between the immune system and the development and progression of AD from the existing literature， with an emphasis on the role of peripheral immunity in both the innate and adaptive immune systems， aiming to provide novel ideas for future research on AD in the immunological direction.
- Full text:2025071013590817395外周免疫在阿尔茨海默病发生发展中作用的研究进展.pdf
