Value of ESRS score combined with inflammatory factors in predicting cerebral small vessel disease in patients with vertigo in Qinghai area， China
10.19845/j.cnki.zfysjjbzz.2024.0206
- VernacularTitle:ESRS评分联合炎症因子对青海地区CSVD预测价值的研究
- Author:
Xiaoyuan ZHU
1
;
Guisheng HAO
2
Author Information
1. 青海大学研究生院，青海 西宁 810000
2. 青海省人民医院，青海 西宁 810000
- Publication Type:Journal Article
- Keywords:
Vertigo;
Cerebral small vessel disease;
ESRS score;
Inflammatory factors
- MeSH:
Vertigo
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(12):1079-1084
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of ESRS score combined with inflammatory factors in predicting cerebral small vessel disease （CSVD） in patients with vertigo in Qinghai area， China. Methods A total of 394 patients who were admitted and diagnosed with vertigo in Department of Neurology， Qinghai Provincial People’s Hospital， from June 2022 to June 2023 were enrolled as subjects， among whom there were 201 patients with central vertigo and 193 patients with peripheral vertigo. Inflammation-related indicators were collected， including neutrophil-to-lymphocyte ratio （NLR）， platelet-to-lymphocyte ratio （PLR）， monocyte to high-density lipoprotein cholesterol ratio， and lymphocyte-to-monocyte ratio， and ESRS score and MRI examination were performed for all patients. Results Among the 201 patients with central vertigo， 118 （58.7%） developed CSVD， and among the 193 patients with peripheral vertigo， 78 （40.4%） developed CSVD. The univariate analysis showed that there were significant differences in systolic blood pressure， NLR， PLR， MHR， LMR， and ESRS score between the patients with CSVD and those without CSVD in the central vertigo group and the peripheral vertigo group， and there were significant differences in age and ESRS score between the central vertigo CSVD group and the peripheral vertigo CSVD group. For the patients with central vertigo， the risk of CSVD in the low-， medium-， and high-risk ESRS score groups was 25.49%， 68.75%， and 100.00%， respectively， and for those with peripheral vertigo， the risk of CSVD in the low-， medium-， and high-risk ESRS score groups was 32.10%， 66.70%， and 100.00%， respectively. The logistic regression analysis showed that ESRS score， NLR， and PLR were independent risk factors for CSVD in patients with vertigo. In the central vertigo group， ESRS score， NLR， and PLR alone had an area under the ROC curve （AUC） of 0.790， 0.721， and 0.635， respectively， in predicting CSVD， and the combination of the three indices had an AUC of 0.846； in the peripheral vertigo group， ESRS score， NLR， and PLR alone had an AUC of 0.757， 0.714， and 0.632， respectively， in predicting CSVD， and the combination of the three indices had an AUC of 0.816. Conclusion The risk of CSVD in patients with vertigo in Qinghai area increases with the increase in ESRS score， and the risk of CSVD in patients with vertigo in Qinghai area is positively correlated with NLR and PLR. ESRS score combined with NLR and PLR is more sensitive than the above indices used alone in the risk assessment of CSVD in patients with vertigo in Qinghai area. The central vertigo CSVD group has a higher ESRS score than the peripheral vertigo CSVD group， suggesting that patients with central vertigo tend to develop CSVD.
- Full text:2025071010270405810ESRS评分联合炎症因子对青海地区CSVD预测价值的研究.pdf
