Miller Fisher syndrome mimicking myasthenia gravis with positive anti-GQ1b，anti-GT1a，and anti-sulfatide antibodies： a case report
10.19845/j.cnki.zfysjjbzz.2024.0031
- VernacularTitle:抗GQ1b、GT1a、Sulfatide抗体阳性的类重症肌无力Miller-Fisher综合征1例报告
- Author:
Tianshu WANG
1
;
Songyan LIU
1
Author Information
1. Department of Neurology，China-Japan Union Hospital of Jilin University，Changchun 130000，China
- Publication Type:Journal Article
- Keywords:
Miller-Fisher syndrome;
Myasthenia gravis;
Anti-GQ1b antibody;
Ophthalmoplegia
- MeSH:
Miller Fisher Syndrome;
Ophthalmoplegia
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(2):161-163
- CountryChina
- Language:Chinese
-
Abstract:
Miller Fisher syndrome（MFS）is a clinical variant of Guillain-Barre syndrome（GBS）and has the main clinical features of ataxia，ophthalmoplegia，and tendon areflexia，with pupil changes and abnormal pupillary light reflex in rare cases. There are generally no symptom fluctuations，and positive anti-GQ1b IgG antibodies can be detected in some patients. This article reports a case of MFS with positive anti-GQ1b，anti-GT1a，and anti-sulfatide antibodies and fluctuating extraocular muscle paralysis as the initial presentation，accompanied by bilateral pupil dilation，delayed light reflex，and numbness and weakness in the limbs. The symptoms are rare and atypical，which may easily lead to misdiagnosis in clinical practice.
- Full text:202507090917488286抗GQ1b、GT1a、Sulfatide抗体阳性的类重症肌无力Miller-Fisher综合征1例报告.pdf
