Research progress on the relationship between leptin and perimenopausal depression
10.19845/j.cnki.zfysjjbzz.2024.0018
- VernacularTitle:瘦素与围绝经期抑郁症的关系及研究进展
- Author:
Wenzhe CUI
1
;
Guangquan LI
1
Author Information
1. The Second Clinical Medical College of Jilin University，Changchun 130062，China
- Publication Type:Journal Article
- Keywords:
Depression;
Perimenopausal period;
Leptin;
Estrogen
- MeSH:
Depression;
Leptin;
Estrogens
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(1):92-96
- CountryChina
- Language:Chinese
-
Abstract:
Perimenopausal period is a period with high incidence of female depression, which shows the symptoms of depressed mood and disturbed mind. The pathogenesis of the disease is not clear and it is urgent to search for efficient treatment. Leptin is a hormone secreted by fat cells and plays a role in both metabolism and neuroprotection. In recent years, leptin has been reported to ameliorate perimenopausal depression, and leptin is closely related to estrogen synthesis and secretion. Therefore, leptin may be used as a potential molecular target for the treatment of perimenopausal depression. In this paper, the research on the relationship between leptin and perimenopausal depression is reviewed.
- Full text:2025070814553428059瘦素与围绝经期抑郁症的关系及研究进展.pdf
