Research advances in the Caspase family and denervated skeletal muscle atrophy
10.19845/j.cnki.zfysjjbzz.2024.0016
- VernacularTitle:Caspase家族与失神经支配骨骼肌萎缩的研究进展
- Author:
Miao TIAN
1
;
Pei CHEN
1
Author Information
1. The First Clinical School of Hubei University of Chinese Medicine， Wuhan 430061， China
- Publication Type:Journal Article
- Keywords:
Caspase family;
Muscular atrophy;
Denervation
- MeSH:
Denervation
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(1):84-87
- CountryChina
- Language:Chinese
-
Abstract:
The Caspase family， short for cysteine-containing aspartate protein hydrolases， can be classified into inflammatory Caspases and apoptotic Caspases according to their role. It has been confirmed that Caspases promote myocyte apoptosis through multiple pathways in denervated skeletal muscle atrophy. In recent years， studies have shown that the pyroptosis pathway dominated by caspase-1 is activated in denervated myocyte atrophy， which is a new direction for exploration that is not mentioned in previous studies. This article reviews the role of the Caspase family in denervated skeletal muscle atrophy.
- Full text:2025070814295736745Caspase家族与失神经支配骨骼肌萎缩的研究进展.pdf
