Differences and similarities in the prevention and treatment of cerebral small vessel disease and stroke
10.19845/j.cnki.zfysjjbzz.2024.0002
- VernacularTitle:脑小血管病与卒中防治的“异”与“同”
- Author:
Ruinan ZHANG
1
;
Yilong WANG
1
Author Information
1. Department of Neurology, Beijing Tiantan Hospital, Capital Medical University/Chinese Institute for Brain Research, Beijing/National Center for Neurological Disorders/Advanced Innovation Center for Human Brain Protection, Capital Medical University/China National Clinical Research Center for Neurological Diseases/Beijing Laboratory of Oral Health/Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100070, China
- Publication Type:Journal Article
- Keywords:
Cerebral small vessel disease;
Stroke;
Magnetic resonance imaging
- MeSH:
Stroke
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(1):7-13
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease is a series of complex and heterogeneous cerebrovascular syndromes caused by various etiological factors that affect small vessels in the brain. Due to a lack of typical symptoms, the diagnosis of cerebral small vessel disease relies mainly on magnetic resonance imaging, and the neuroimaging findings can include recent small subcortical infarcts, lacunes of presumed vascular origin, white matter hyperintensities of presumed vascular origin, perivascular spaces, cerebral microbleeds, cortical superficial siderosis, and brain atrophy. Currently, the pathogenic mechanism of cerebral small vessel disease remains unclear, and specific treatment is also lacking. Given its similarities with stroke in risk factors and histopathological characteristics, stroke prevention and treatment approaches, such as antihypertensive and antiplatelet therapies, can be applied to the treatment of cerebral small vessel disease. However, due to the differences between the two conditions, stroke treatments cannot be fully suitable for cerebral small vessel disease, and an individualized comprehensive assessment is needed. This review presents the management of cerebral small vessel disease and stroke, highlighting their similarities and differences.
- Full text:2025070810234819412脑小血管病与卒中防治的“异”与“同”.pdf