Research and application of exosomes in the diagnosis and treatment of ischemic stroke
10.19845/j.cnki.zfysjjbzz.2024.0001
- VernacularTitle:外泌体在缺血性卒中诊断及治疗中的研究与应用
- Author:
Wenjing YIN
1
;
Zhenni GUO
1
;
Yi YANG
1
Author Information
1. Stroke Center， The Neurology Hospital， The First Hospital of Jilin University，Changchun 130021， China
- Publication Type:Journal Article
- Keywords:
Ischemic stroke;
Exosome;
Diagnosis;
Treatment;
Drug delivery
- MeSH:
Exosomes;
Diagnosis
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(1):3-6
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke （IS） is the most common type of stroke that can lead to severe neurological dysfunction while effective diagnostic and therapeutic methods are currently limited. Exosomes are natural vesicles that can play a key role in intercellular communication by delivering proteins， lipids， and nucleic acids. Notably，IS could cause changes in the level and content of exosome， which can serve as a potential biomarker to assist the diagnosis and treatment of IS. This article reviews the potential diagnostic value of exosomes，discusses their repair effects， and explores the potential application as drug carriers in IS. We also provide a concise summary of the current clinical research status based on exosomes.
- Full text:2025070810084950373外泌体在缺血性卒中诊断及治疗中的研究与应用.pdf
