Clinical observation on Jiu-Wei-Yong-An granule combined with cetirizine in the treatment of eczema with damp-heat accumulation of skin syndrome
10.12206/j.issn.2097-2024.202407045
- VernacularTitle:九味永安颗粒联合西替利嗪治疗湿疹湿热蕴肤证的临床疗效观察
- Author:
Yuanyuan MENG
1
;
Yunyang WU
2
;
Tingru CHEN
1
;
Qinwufeng GU
1
;
Yanlong YANG
2
Author Information
1. Department of Surgery of Traditional Chinese Medicine, the First Affiliated Hospital.
2. Department of Surgery of Traditional Chinese Medicine, The First Affiliated Hospital, b.Teaching and Research office of Surgery of Traditional Chinese Medicine, Naval Medical University, Shanghai 200433, China.
- Publication Type:Medicine&Clinical
- Keywords:
eczema;
damp-heat accumulation;
Jiu-Wei-Yong-An granules;
eczema area and severity index
- From:
Journal of Pharmaceutical Practice and Service
2025;43(6):298-302
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect of Jiu-Wei-Yong-An granule combined with cetirizine in the treatment of damp-heat accumulation syndrome of eczema. Methods 108 eczema patients with syndrome of damp-heat accumulated in the skin, treated in the Department of Traditional Chinese Surgery in the First Affiliated Hospital of Naval Medical University from December 2021 to March 2023, were selected. They were randomly divided into an observation group and a control group, 54 cases in each. Both groups took cetirizine tablets orally for basic treatment. The observation group was given Jiu-Wei-Yong-An granules, and the control group was given placebos of the same. The clinical efficacy before and after treatment in the two groups was observed and compared, including TCM syndrome scores, eczema area and severity index （EASI）, visual analogue scale （VAS）, and adverse reactions. Results After treatment, the total effective rate of the observation group （88.9%） was higher than that of the control group （77.8%）, and the difference was statistically significant （P<0.05）. After treatment, the TCM syndrome score, EASI and VAS in the observation group were significantly lower than those in the control group （P<0.05）, and the difference was statistically significant. There was no significant difference in the total rate of adverse reactions between the two groups （P>0.05）. Conclusion The combination of Jiu-Wei-Yong-An granules and cetirizine tablets in the treatment of damp-heat eczema showed significantly better clinical outcomes in the observation group compared to the control. It effectively improved patient conditions, reduced skin lesion areas, and alleviated itching, with both safety and efficacy that merit clinical promotion.
