Analysis of chloroplast genomes from Salvia miltiorrhiza and its congeneric species
10.12206/j.issn.2097-2024.202504023
- VernacularTitle:丹参及其近缘物种的叶绿体基因组分析
- Author:
Jindong YANG
1
;
Zhenxi FANG
2
;
Chengyang NIE
1
;
Ruibing CHEN
1
;
Qing LI
3
;
Lei ZHANG
1
Author Information
1. School of Pharmacy, Naval Medical University, Shanghai 200433, China.
2. Department of Pharmacy, Shanghai General Hospital Jiading Branch, Shanghai 201821, China.
3. Department of Pharmacy, the Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China.
- Publication Type:Originalarticles
- Keywords:
Salvia miltiorrhiza Bunge;
Salvia;
chloroplast genome;
sequence characterization;
phylogenetic analysis
- From:
Journal of Pharmaceutical Practice and Service
2025;43(6):275-282
- CountryChina
- Language:Chinese
-
Abstract:
Salvia miltiorrhiza Bunge （Lamiaceae） is a medicinal plant widely used in Traditional Chinese Medicine for treating cardiovascular and cerebrovascular diseases. Chloroplasts are double-membrane-bound, chlorophyll-containing organelles and responsible for photosynthesis in plant cells. The structural information of chloroplast genomes serves as the foundation for precise exogenous gene insertion, site selection, and chloroplast genome modification. In this study, a comprehensive analysis and comparison of 125 chloroplast genomes from S. miltiorrhiza and 76 congeneric species were conducted, focusing on sequence characteristics, codon usage bias, simple sequence repeats （SSRs）, contraction/expansion of chloroplast genome boundaries, and phylogenetic relationships, which could provide a theoretical foundation for advancing chloroplast genetic engineering, genetic diversity analysis, molecular breeding, and species identification within the Salvia genus.
