A Case of Refractory Oral Aphthous Ulcer Successfully Treated with Adalimumab.
10.4078/jrd.2017.24.3.157
- Author:
Jinyeong KIM
1
;
Myung jin SONG
;
Hye Jin JEONG
;
Soo Kyung CHO
;
Yoon Kyoung SUNG
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. sungyk@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Oral ulcer;
Aphthous stomatitis;
Tumor necrosis factor-alpha inhibitor;
Adalimumab
- MeSH:
Adalimumab*;
Analgesics;
Anti-Infective Agents, Local;
Humans;
Necrosis;
Oral Ulcer;
Quality of Life;
Stomatitis, Aphthous*;
Ulcer
- From:Journal of Rheumatic Diseases
2017;24(3):157-160
- CountryRepublic of Korea
- Language:English
-
Abstract:
Oral aphthous ulcer is a common lesion characterized by loss of dermal tissue of various shapes in many diseases. It is not serious, but may affect quality of life through pain and discomfort. In many cases, it heals spontaneously without treatment or with topical agents such as antiseptics, analgesics and corticosteroid in a few days. However, rarely, there are a few cases of aphthous ulcer that remain refractory despite appropriate treatment. Tumor necrosis factor-α inhibitors have recently been used in treatment of severe mucosal ulcer in Behçet's disease. Herein, we report a patient suffering from refractory oral aphthous ulcers that were resistant to topical and systemic agents, but were successfully treated with adalimumab.
