Effects of perioperative goal-directed fluid therapy on hemodynamics, postoperative recovery and complications in elderly patients with gastric cancer radical surgery complicated by hypertension
- VernacularTitle:围术期目标导向液体治疗对老年胃癌根治术伴高血压患者血流动力学、术后恢复及并发症的影响
- Author:
Juan CHEN
1
;
Xiaoling LI
;
Shaofei CHENG
;
Junde HOU
;
Yongxue CHEN
;
Fei LI
Author Information
- Publication Type:Research Article
- Keywords: gastric cancer radical surgery; hypertension; goal-directed fluid therapy; hemodynamics; postoperative recovery; complications
- From: Journal of Clinical Medicine in Practice 2024;28(15):105-109
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of perioperative goal-directed fluid therapy (GDFT) on hemodynamics, postoperative recovery, and complications in elderly patientswith gastric cancer radical surgery complicated by hypertension. Methods A total of 88 elderly patients with gastric cancer radical surgery complicated by hypertension were enrolled and randomly divided into treatment group and control group, with 44 patients in each group. The treatment group received GDFT during the perioperative period, while the control group received conventional fluid therapy. The mean arterial pressure, heart rate, and central venous oxygen saturation (ScvO2) at different time points, as well as postoperative exhaust time, postoperative hospital stay, and postoperative complication rates were compared between the two groups. Results The time effects (
F =60.488, 49.789, 39.423), intergroup effects (F =17.317, 12.969, 10.101), and interaction effects (F =26.415, 22.546, 17.294) of mean arterial pressure, heart rate, and ScvO2 in the two groups showed statistically significant difference(P < 0.05). After surgery, the mean arterial pressure, heart rate, and ScvO2 in the treatment group were higher than those before anesthesia and the control group (P < 0.05). The postoperative exhaust time and hospital stay in the treatment group were (2.25±0.61) and (10.29±1.96) days, respectively, which were shorter than (2.82±0.71) and (12.36±2.29) days in the control group (P < 0.05). The total incidence of postoperative complications in the treatment group was lower than that in the control group (11.36% versus 29.54%,P < 0.05). Conclusion Applying GDFT during the perioperative period for elderly patients with gastric cancer radical surgery complicated by hypertension can provide a more stable hemodynamic environment, improve tissue perfusion, accelerate postoperative recovery, and reduce postoperative complications.
