Research progress on neuroprotective effect and mechanism of spermidine
- VernacularTitle:亚精胺的神经保护作用及机制的研究进展
- Author:
Chaoyong WANG
1
;
Deyan CHEN
;
Shuangshi WU
;
Binjia RUAN
;
Wanda ZHAN
;
Fanhao WEI
;
Yongxiang WANG
Author Information
- Publication Type:Research Article
- Keywords: spermidine; polyamine metabolism; neurological damage disease; neuroprotection; research progress
- From: Journal of Clinical Medicine in Practice 2024;28(2):124-128
- CountryChina
- Language:Chinese
- Abstract: Spermidine, as a natural polyamine with high content in nerve cells, plays roles in regulating synaptic plasticity, promoting autophagy, and alleviating oxidative stress in the nervous system. Spermidine and polyamine metabolism may bring new therapeutic ideas for nervous system injury diseases. This paper reviewed the neuroprotective effects and mechanisms of spermidine in nervous system injury diseases.
