Evaluating the chromosome mutagenicity of nuciferin
- Author:
Nhung Thi Nguyen
- Publication Type:Journal Article
- Keywords:
chromosomal mutagenicity
- MeSH:
Aporphines;
Chromosomes
- From:Journal of Medical Research
2000;14(1):25-29
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Nuciferin, a chemical extracted from the leaves of Nelumbo nucifera Gaerth. Chromosome mutagenicity of nuciferin was evaluated in bone marrow cells and testicular cells of 30 mice. Chromosome preparation were sampled 24h after injection of nuciferin. 2880 metaphases from bone marrow cells and 2720 metaphases diakinesis from testicular cells were analyzed. The frequency of cells with numerical and structural chromosome aberrations of treated mice showed no significant difference than that found in the control. The result obtained on the study suggested that nuciferin did not exert any chromosome mutagenicity.
