Sick Sinus Syndrome Following Severe Hyponatremia Associated with Desmopressin Therapy.
10.3904/kjm.2015.89.5.558
- Author:
Young Seok SOHN
1
;
Min Ku KANG
;
Young Il KIM
;
Jun Han LEE
;
Jin Kyu PARK
;
Soon Gil KIM
;
Jeong Hun SHIN
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. cardio.hyapex@gmail.com
- Publication Type:Case Report
- Keywords:
Deamino arginine vasopressin;
Hyponatremia;
Sick sinus syndrome
- MeSH:
Aged;
Arginine Vasopressin;
Deamino Arginine Vasopressin*;
Diabetes Insipidus;
Humans;
Hyponatremia*;
Nocturnal Enuresis;
Polyuria;
Sick Sinus Syndrome*
- From:Korean Journal of Medicine
2015;89(5):558-562
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Desmopressin diacetate arginine vasopressin (DDAVP) is a synthetic analogue of the arginine vasopressin that is widely used in the treatment of diabetes insipidus, nocturnal enuresis, and polyuria. Although it is generally well-tolerated, DDAVP can cause hyponatremia, especially in elderly patients. There are many reports of DDAVP-induced hyponatremia, but there has been only one case report in which sinus node dysfunction was caused by severe hyponatremia. Here we report a case of sick sinus syndrome that occurred during an episode of severe hyponatremia induced by chronic use of desmopressin in a 91-year-old man who had nocturnal enuresis.
