Fever-Induced QTc Prolongation and Ventricular Fibrillation in a Healthy Young Man.
10.3349/ymj.2011.52.6.1025
- Author:
Sun Min LIM
1
;
Hui Nam PAK
;
Moon Hyoung LEE
;
Sung Soon KIM
;
Boyoung JOUNG
Author Information
1. Division of Cardiology, Yonsei Cardiovascular Center and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, Korea. cby6908@yuhs.ac
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Sudden cardiac death;
long QT syndrome;
fever
- MeSH:
Adult;
Electrocardiography;
Fever/*complications;
Humans;
Long QT Syndrome/*diagnosis/*etiology;
Male;
Ventricular Fibrillation/*diagnosis/*etiology
- From:Yonsei Medical Journal
2011;52(6):1025-1027
- CountryRepublic of Korea
- Language:English
-
Abstract:
Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope, seizure, and sudden death. Congenital long QT syndrome is a genetic disorder, characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.