Treatment of Recalcitrant Acquired Reactive Perforating Collagenosis with Low-dose Allopurinol.
- Author:
Mi Seon SHIN
1
;
Doo Rak LEE
;
Mi Youn PARK
Author Information
1. Department of Dermatology, National Medical Center, Seoul, Korea. younskin@naver.com
- Publication Type:Case Report
- Keywords:
Acquired reactive perforating collagenosis;
Allopurinol
- MeSH:
Adult;
Allopurinol*;
Collagen;
Diabetes Mellitus;
Diabetic Nephropathies;
Humans;
Hypothyroidism;
Kidney Failure, Chronic;
Renal Insufficiency
- From:Korean Journal of Dermatology
2007;45(11):1230-1232
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Reactive perforating collagenosis is one of a range of essential perforating disorders and is characterized by the transepithelial elimination of altered collagen. Two types have been recognized: the inherited, or childhood form and the acquired, or adult form. Acquired reactive perforating collagenosis is associated with systemic diseases, especially diabetes mellitus and/or renal failure. We report that a low-dose allopurinol showed dramatic effects on acquired reactive perforating collagenosis, which was associated with hypothyroidism and chronic renal failure caused by diabetic nephropathy.
