Detection of Human Papillomaviruses DNA in Genital Wart - like Lesions.
- Author:
Joo Hyun CHOI
;
Kyoung Chan PARK
;
Un Cheol YEO
;
Jeong Aee KIM
;
Yoo Shin LEE
;
Kye Yong SONG
- Publication Type:Original Article
- MeSH:
Condylomata Acuminata*;
DNA*;
Humans*;
In Situ Hybridization
- From:Korean Journal of Dermatology
1990;28(4):445-449
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In situ hybridization using biotinylated HPV(Human papillomaviruses) probes was performed to detect HPV DNA in 24 patients with genital wart-like lesions. The lesions were divided into two groups, with or without dysplastic changes histologically. We could detect HPV6/11 in 13 of 17 lesions(76.5%) without dysplastic changes. HPU16/18 was detected in a case with dysplastic changes. HPV6/ll was also detected in a case considered to be misdiagnosed as bowenoid papulosis. Oncogenic HPV such as HPV16/18 was found in one of histologically splastic lesions(14.3%).
