Comparative Analysis of Radiologically Measured Size and True Size of Renal Tumors.
10.4111/kju.2013.54.11.738
- Author:
Kook Bin LEE
1
;
Sun Il KIM
;
Dae Sung CHO
;
Seong Kon PARK
;
Hyun Ik JANG
;
Se Joong KIM
Author Information
1. Department of Urology, Ajou University School of Medicine, Suwon, Korea. sejoong@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Kidney;
Neoplasms;
Pathology;
Radiology
- MeSH:
Carcinoma, Renal Cell;
Humans;
Kidney;
Nephrectomy
- From:Korean Journal of Urology
2013;54(11):738-743
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We evaluated the differences between radiologically measured size and pathologic size of renal tumors. MATERIALS AND METHODS: The data from 171 patients who underwent radical or partial nephrectomy for a renal tumor at Ajou University Hospital were reviewed. Radiologic tumor size, which was defined as the largest diameter on a computed tomographic scan, was compared with pathologic tumor size, which was defined as the largest diameter on gross pathologic examination. RESULTS: Mean radiologic size was significantly larger than mean pathologic size for all tumors (p=0.019). When stratified according to radiologic size range, mean radiologic size was significantly larger than mean pathologic size for tumors <4 cm (p=0.003), but there was no significant difference between the sizes for tumors 4-7 cm and >7 cm. When classified according to histologic subtype, mean radiologic size was significantly larger than mean pathologic size only in clear cell renal cell carcinomas (p=0.002). When classified according to tumor location, mean radiologic size was significantly larger than mean pathologic size in endophytic tumors (p=0.043) but not in exophytic tumors. When endophytic tumors were stratified according to radiologic size range, there was a significant difference between the mean radiologic and pathologic sizes for tumors <4 cm (p=0.001) but not for tumors 4-7 cm (p=0.073) and >7 cm (p=0.603). CONCLUSIONS: Our results suggest that in planning a nephron-sparing surgery for renal tumors, especially for endophytic tumors of less than 4 cm, the tumor size measured on a computed tomography scan should be readjusted to get a more precise estimate of the tumor size.