Neuronal Intranuclear Inclusion Disease Presented with Acute Aphasia
- Author:
Jinyong KIM
1
;
Su-Hyun PARK
;
Hye-Rim SHIN
Author Information
- Publication Type:Case Report
- From:Journal of the Korean Neurological Association 2024;42(4):348-352
- CountryRepublic of Korea
- Language:Korean
- Abstract: Neuronal intranuclear inclusion disease (NIID) is a rare disorder with slowly progressive neurodegeneration. Major clinical presentation is dementia, but some patients can have episodic symptoms. This is a rare case of NIID presented with acute aphasia. A 62-years-old male visited emergency room presenting with aphasia. On brain magnetic resonance imaging, a U-shaped diffusion high signal intensity lesion in bilateral frontal corticomedullary junction was observed. A skin biopsy showed intranuclear cytoplasmic inclusion bodies, so he was diagnosed as NIID.
