A Comparison between Propofol and Thiopental for Induction of Anesthesia for Elective Caesarean Section.
10.4097/kjae.1992.25.2.297
- Author:
Sae Jin CHOI
1
;
Jin Ho BAE
;
Neung Hee HAN
;
Soo Chang SON
Author Information
1. Department of Anesthesiology, College of Medicine, Chungnam National University, Taejeon, Korea.
- Publication Type:Original Article
- Keywords:
Caesarean section;
Propofol;
Thiopental
- MeSH:
Anesthesia*;
Anesthesia, General;
Arterial Pressure;
Blood Gas Analysis;
Cesarean Section*;
Female;
Heart Rate;
Humans;
Infant, Newborn;
Pregnancy;
Propofol*;
Reference Values;
Thiopental*
- From:Korean Journal of Anesthesiology
1992;25(2):297-301
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thiopental sodium has been used in anesthesia of Caesarean section since 1936 and is regarded as the standard induction agent. Propofol has properties which suggest that it might be a useful alternative to thiopental. We compared propofol with thiopental for induction of anesthesia in elective Caesarean section in the present study. Particular attentaion was paid to induction characterisitics and the neonatal effects of both agents. The results were as follows. 1) Side effect during induction were rare in both groups. But both agents caused mild discomfort on injection. 2) There were significant increase in systemic arterial pressure, diastoric pressure and heart rate at postintubation I minute in both groups. But there were no significant differences in cardio vascular response between both groups during the induction. 3) The Apgar scores of the neonates did not differ significantly, and the blood gas analyses of neonates were within the normal range in both groups. We conclude that propofol, in a dose of 2.5 mg/kg, is an acceptable alternative to thiopental for the induction of general anesthesia in Caesarean section.
