Allergic Contact Dermatitis with Doxepin Hydrochloride Cream.
- Author:
Soo Jin AHN
1
;
Do Young RHEE
;
Sung Eun CHANG
;
Ho Seok SUH
;
Mi Woo LEE
;
Jee Ho CHOI
;
Kee Chan MOON
;
Jai Kyoung KOH
;
So Hyung KIM
Author Information
1. Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. cse@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Contact dermatitis;
Doxepin hydrochloride
- MeSH:
Dermatitis, Allergic Contact*;
Dermatitis, Contact;
Doxepin*;
Eczema;
Edema;
Neck;
Phenothiazines
- From:Korean Journal of Dermatology
2006;44(2):185-186
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Doxepin hydrochloride cream with potent H1 and H2 blocker activity is a tricyclic antidepressant, which is structurally similar to phenothiazines, and also known to be a contact sensitizer and photosensitizer. We report a case of allergic contact dermatitis due to doxepin hydrochloride cream in a 75-year-old-man, who developed facial edema and eczema at the application sites (face, neck and upper trunk) within several hours of application of doxepin hydrochloride cream. Clinicians should be aware of the possibility of allergic contact dermatitis to doxepin cream, if the condition worsens with use of this medication.
