A Case of Continuous Venovenous Hemodiafiltration in the Treatment of Neonatal Hyperammonemia Due to Methylmalonic Acidemia.
- Author:
Won Kyoung JHANG
1
;
Hye Won HAHN
;
Young Lim SHIN
;
Hyun Kyung PARK
;
Ai Rhan KIM
;
Young Seo PARK
;
Han Wook YOO
Author Information
1. Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. yspark@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Continuous venovenous hemodiafiltration;
Hyperammonemia;
Neonate;
Methylmalonic acidemia
- MeSH:
Ammonia;
Brain;
Central Nervous System;
Emergencies;
Female;
Hemodiafiltration*;
Humans;
Hyperammonemia*;
Infant, Newborn
- From:Journal of the Korean Society of Pediatric Nephrology
2003;7(1):96-102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute hyperammonemia is a medical emergency in the newborn. Efficient, prompt removal of serum ammonia is essential in preventing irreversible brain damage in order to prevent the profound central nervous system dysfunction due to hyperammonia. We report a case of 2.3 kg, 5-day old girl with methylmalonic acidemia who presented with severe hyperammonemia and was successfully treated with continuous venovenous hemodiafiltration(CVVHDF). CVVHDF is an effective and safe method of ammonia removal in the newborn.
