A Case of Churg-Strauss Syndrome Showing Severe Skin Necrosis.
- Author:
Myung IM
1
;
Yong Hee NAM
;
Young Joon SEO
;
Jeung Hoon LEE
;
Jang Kyu PARK
Author Information
1. Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea. joon@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Churg-Strauss syndrome;
Skin necrosis
- MeSH:
Aged;
Antibodies, Antineutrophil Cytoplasmic;
Asthma;
Buttocks;
Churg-Strauss Syndrome*;
Diagnosis;
Eosinophilia;
Extremities;
Female;
Fever;
Granuloma;
Humans;
Necrosis*;
Prednisolone;
Skin*;
Systemic Vasculitis
- From:Korean Journal of Dermatology
2006;44(2):216-219
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Churg-Strauss syndrome is a disorder characterized by asthma, fever, systemic vasculitis, extravascular granulomas and hypereosinophilia. A 70-year-old woman with a 2-year history of bronchial asthma was admitted to hospital, due to extensive hemorrhagic bullae embedded in necrotic tissue on both extremities, the buttocks and trunk. The patient showed abnormal laboratory findings including significant peripheral blood eosinophilia and p-ANCA (+), and histopathologically leukocytoclastic vasculitits with marked eosinophlilic infiltration. Based on the clinical course, laboratory data and pathologic findings, the diagnosis of Churg-Strauss syndrome was made. Treatment with oral prednisolone was started, and the clinical findings improved.
