Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study
10.3393/ac.2024.00570.0081
- Author:
Antonio BRILLANTINO
1
;
Luigi MARANO
;
Maurizio GRILLO
;
Alessio PALUMBO
;
Fabrizio FORONI
;
Luciano VICENZO
;
Alessio ANTROPOLI
;
Michele LANZA
;
Maria Laura Sandoval SOTELO
;
Nicola SANGIULIANO
;
Mauro MAGLIO
;
Rosanna FILOSA
;
Lucia ABBATIELLO
;
Maria Preziosa ROMANO
;
Luana PASSARIELLO
;
Pasquale TALENTO
;
Giovanna IOIA
;
Corrado RISPOLI
;
Mariano Fortunato ARMELLINO
;
Vincenzo BOTTINO
;
Adolfo RENZI
;
Carlo BARTONE
;
Luigi MONACO
;
Paolino MAURO
;
Stefano PICARDI
;
Maria Paola MENNA
;
Elisa PALLADINO
;
Mario Massimo MENSORIO
;
Vinicio MOSCA
;
Claudio GAMBARDELLA
;
Luigi BRUSCIANO
;
Ludovico DOCIMO
Author Information
1. Department of General Surgery, Antonio Cardarelli Hospital, Naples, Italy
- Publication Type:Original Article
- From:Annals of Coloproctology
2024;40(6):602-609
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:Postoperative pain is a major concern for patients undergoing ultrasound scalpel-assisted hemorrhoidectomy, potentially exacerbated by delayed wound healing. This study aimed to evaluate the impact of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and other anti-inflammatory agents (Antroclean Fisioderm) on postoperative pain, itching, and wound healing in patients who had undergone this procedure.
Methods:This multicenter observational case-control study involved a cohort of consecutive adult patients who underwent hemorrhoidectomy using an ultrasound device. The study compared 2 different postoperative wound management strategies over 1 month after surgery: washing with warm water twice per day (control group) versus a 2-minute topical application of intimate cleansing gel (Antroclean Fisioderm) followed by a warm water wash (intervention group).
Results:The median postoperative pain score was significantly lower in the intervention group than in the control group at each follow-up point (P<0.01). The percentage of patients reporting anal itching was also significantly lower in the intervention group than in the control group at each follow-up point (P<0.01). All patients in the intervention group achieved complete wound healing 4 weeks after surgery, compared to 88 (82%) in the control group (P<0.01). No adverse events were reported.
Conclusion:The topical application of intimate cleansing gel (Antroclean Fisioderm) twice daily for 1 month following ultrasound scalpel-assisted hemorrhoidectomy appears to be associated with faster healing, reduced pain, decreased itching, and improved quality of life, without any adverse effects. Further larger and prospective randomized trials are recommended to confirm these findings.
