Experimental infection of dogs with highly pathogenic avian influenza virus (H5N8).
10.4142/jvs.2017.18.S1.381
- Author:
Seong Su YUK
1
;
Dong Hun LEE
;
Jae Keun PARK
;
Erdene Ochir TSEREN-OCHIR
;
Jung Hoon KWON
;
Jin Yong NOH
;
Chang Seon SONG
Author Information
1. Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea. songcs@konkuk.ac.kr
- Publication Type:Brief Communication
- Keywords:
animal experiment;
dogs;
influenza A virus H5N8 subtype;
transmission;
virulence
- MeSH:
Agriculture;
Animal Experimentation;
Animals;
Dogs*;
Genes, Viral;
Influenza in Birds*;
Korea;
Mammals;
Seroconversion;
Virulence
- From:Journal of Veterinary Science
2017;18(S1):381-384
- CountryRepublic of Korea
- Language:English
-
Abstract:
During the highly pathogenic avian influenza (HPAI) H5N8 virus outbreak in Korea, a dog in layer farm contaminated by H5N8 was reported seropositive for HPAI H5N8. To investigate the possibility of adaptation and transmission of HPAI H5N8 to dogs, we experimentally inoculated dogs with H5N8. Viral genes were weakly detected in nasal swabs and seroconversions in inoculated and contact dogs. Although the H5N8 virus did not induced severe clinical signs to dogs, the results suggest that surveillance of farm dogs should continue as a species in which the avian influenza virus may acquire infectivity to mammals through frequent contact with the virus.
