Efficacy comparison of pars plana vitrectomy with or without inner limiting membrane peeling in refractory diabetic macular edema
10.3980/j.issn.1672-5123.2025.7.19
- VernacularTitle:玻璃体切割术联合或不联合内界膜剥除术治疗顽固性糖尿病黄斑水肿的疗效对比
- Author:
Xiangying LUO
1
,
2
;
Ting XI
1
,
2
;
Dan HUANG
1
,
2
;
Zheyao GU
1
,
2
Author Information
1. The Affiliated Suzhou Hospital of Nanjing Medical University
2. Suzhou Municipal Hospital, Suzhou 215000, Jiangsu Province, China
- Publication Type:Journal Article
- Keywords:
refractory diabetic macular edema;
pars plana vitrectomy;
inner limiting membrane peeling;
efficacy
- From:
International Eye Science
2025;25(7):1147-1151
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the efficacy of pars plana vitrectomy(PPV)with or without inner limiting membrane(ILM)peeling in refractory diabetic macular edema.METHODS:Totally 80 patients with refractory diabetic macular edema were retrospectively selected and assigned into groups according to the treatment method. Among them, 38 patients treated with PPV were included as group A, and 42 patients treated with PPV combined with ILM peeling were included as group B. The relevant data of patients in the two groups were collected, and the efficacy of the two groups was compared.RESULTS: At 1, 3, and 6 mo after surgery, the best corrected visual acuity(BCVA), central macular thickness(CMT), and severity of macular edema in the group B were all superior to those in the group A(all P<0.05). At 6 mo after the surgery, the incidence of complications in the group B was 12%, with no prominent difference compared to 18% of the group A(P>0.05).CONCLUSION:PPV combined with or without ILM peeling can improve visual function and relieve macular edema in patients with refractory diabetic macular edema. However, the combination of PPV and ILM peeling is superior to PPV alone in improving vision and relieving macular edema, and does not increase postoperative complications.
