Effectiveness of Traditional Chinese Medicine Chronic Disease Management Programme after Colorectal Polyp Surgery：A Retrospective Cohort Study
10.13288/j.11-2166/r.2025.12.009
- VernacularTitle:结直肠息肉术后中医慢病管理方案成效的回顾性队列研究
- Author:
Jiahao MO
1
;
Yi CHENG
2
;
Chang LIU
1
;
Peixin HU
2
;
Cailing ZHONG
2
;
Beiping ZHANG
2
Author Information
1. The Second Clinical Medical College of Guangzhou University of Chinese Medicine，Guangzhou，510405
2. Guangdong Provincial Hospital of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
colorectal polyp;
traditional Chinese medicine chronic disease management;
polyp recurrence;
spleen deficiency and dampness stasis syndrome;
influence factor;
retrospective study
- From:
Journal of Traditional Chinese Medicine
2025;66(12):1241-1248
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the effectiveness of traditional Chinese medicine （TCM） chronic disease management programme in preventing postoperative recurrence of colorectal polyps. MethodsThe clinical data of 447 postoperative colorectal polyp patients were retrospectively collected， and the patients were divided into an exposure group and a control group taking the acceptance of TCM chronic disease management programme as exposure factor， and the polyp recurrence rate as the main outcome indicator， comparing the differences in baseline characteristics， outcome events， and safety assessment between the two groups， and conducting correlation analysis between the length of medication and polyp recurrence. Multifactorial logistic regression was used to analyse the effects of receiving the TCM chronic disease management programme （TCM treatment and life management for spleen deficiency and dampness stasis syndrome， dampness and stasis obstruction in collaterals syndrome， and intestinal dampness and heat syndrome）， gender， age， co-morbidities， TCM syndrome， and dietary and exercise factors on the outcome events. ResultsAmong 257 postoperative patients with colorectal polyps， there were 172 in the exposure group and 85 in control group. The recurrence rate of polyps in exposure group was 22.7% （39/172）， while the recurrence rate in control group was 57.6% （49/85）， and the difference between groups was statistically significant （P＜0.01）. The diameter of recurrent polyps in exposure group （median= 4.0 mm） was smaller than that in control group （median= 5.0 mm， P＜0.01）. The correlation analysis between the duration of medication taking and the recurrence of polyps in the spleen deficiency and dampness stasis syndrome group showed Phi value as -0.345 （P＜0.001）； the correlation analysis within the group of dampness and stasis obstruction in collaterals syndrome showed Phi value as -0.361 （P＜0.05）， indicating a negative correlation between the duration of medication taking and polyp recurrence. The results of multivariate logistic regression analysis indicated that the positive effect of accepting TCM chronic disease management programme on preventing polyp recurrence is statistically significant （OR=0.224， P＜0.01）. ConclusionAccepting TCM chronic disease management programme for colorectal polyps can help reducing the recurrence rate after polyp surgery， which is a protective factor for patients to the outcome event.
