Interpretation of guideline for diagnosis and treatment of acute-on-chronic liver failure （2025 edition）

VernacularTitle:《慢加急性肝衰竭诊治指南（2025年版）》解读
Author: Manman XU ¹ ; Huaibin ZOU ¹ ; Zhongping DUAN ¹ ; Tao HAN ² ; Yu CHEN ¹
Author Information

1. Fourth Department of Liver Disease Center， Beijing YouAn Hospital， Capital Medical University， Beijing 100069， China
2. Department of Gastroenterology， The First Affiliated Hospital of Nankai University （Tianjin People’s Hospital）， Tianjin 300121， China
Publication Type:Journal Article
Keywords: Acute-On-Chronic Liver Failure; Diagnosis; Therapeutics; Practice Guidelines as Topic
From: Journal of Clinical Hepatology 2025;41(5):844-850
CountryChina
Language:Chinese
Abstract: In 2025， Severe Liver Disease and Artificial Liver Group and Nutrition and Regeneration in End-Stage Liver Disease Group of Chinese Society of Hepatology， Chinese Medical Association， convened a panel of national experts to jointly develop China’s first guideline for the diagnosis and treatment of acute-on-chronic liver failure （ACLF）. Based on the latest research findings and clinical practice in China and globally， this guideline establishes a standardized definition of ACLF and provide recommendations for its diagnosis， treatment， and clinical management. This article gives an interpretation of the key points in the guideline， in order to provide a reference for standardized diagnosis and treatment of ACLF.