A Case Of Transient Hyporeninemic Hypoaldosteronism After Unilateral Adrenalrectomy for Aldosterone-Producing Adenoma.
10.3803/jkes.2005.20.5.502
- Author:
Jungho SUH
1
;
Gwanpyo KOH
;
Keun Yong PARK
;
Jongwook HONG
;
Suk CHON
;
Seungjoon OH
;
Jeong taek WOO
;
Sung Woon KIM
;
Jin Woo KIM
;
Young Seol KIM
Author Information
1. Department of Internal medicine, Kyung Hee university College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Aldosterone-producing adenoma;
Adrenalectomy;
Hypoaldosteronism
- MeSH:
Adenoma*;
Adrenal Cortex;
Adrenalectomy;
Aldosterone;
Axis, Cervical Vertebra;
Follow-Up Studies;
Furosemide;
Humans;
Hyperaldosteronism;
Hyperkalemia;
Hyperplasia;
Hypertension;
Hypoaldosteronism*;
Hypokalemia;
Plasma;
Renin
- From:Journal of Korean Society of Endocrinology
2005;20(5):502-506
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary aldosteronism is due to either a unilateral adrenal adenoma or bilateral hyperplasia of the adrenal cortex in most cases. A unilateral adrenalectomy in hypertensive and hypokalemic patients, with a well-documented adrenal adenoma, is usually followed by the correction of hypokalemia in all subjects, with the cure of hypertension in 60 to 87% of patients. Here, a unique case, in which a unilateral adrenalectomy for the removal of an adrenal adenoma was followed by severe hyperkalemia, low levels of plasma renin activity and serum aldosterone, suggestive of chronic suppression of the renin-aldosterone axis, is reported. In a follow-up Lasix stimulation test on the 70th day after surgery, the suppression of the renin-aldosterone axis was resolved, indicating the suppression was transient. Patients undergoing a unilateral adrenalectomy for an aldosterone-producing adenoma should be closely followed up to avoid severe hyperkalemia.
