A case of Methimazole-Induced Cholestatic Jaundice With Agranulocytosis.
10.3803/jkes.2005.20.5.519
- Author:
Sang Gu KANG
1
;
Jong Oh BAE
;
Eun Young LEE
;
Seong Min LIM
;
Sang Kun CHO
;
Ji Hye KIM
;
Sun Kyung SONG
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Cheonju, Korea.
- Publication Type:Case Report
- Keywords:
Methimazole;
Cholestatic jaundice;
Agranulocytosis
- MeSH:
Agranulocytosis*;
Exanthema;
Humans;
Jaundice, Obstructive*;
Leukopenia;
Methimazole
- From:Journal of Korean Society of Endocrinology
2005;20(5):519-523
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Methimazole is a widely used and generally well-tolerated antithyroid agent. Adverse reactions occur in 1~5% of patients taking methimazole medication, but these are most commonly transient, benign leukopenia and a skin rash. Severe cholestatic jaundice, combined with agranulocytosis, has been known as a rare complication. Herein, a case of methimazole induced cholestatic jaundice, with agranulocytosis, is reported.
