Two cases of massive fetomaternal hemorrhage treated by exchange transfusion.
- Author:
Chang Hyun LEE
1
;
Jae Kwang KIM
;
Myung Ki HAN
;
Jeung wook KIM
;
Jung Ju LEE
Author Information
1. Department of Pediatrics, College of Ulsan, Gangneung Asan Hospital, Gangneung, Korea.
- Publication Type:Case Report
- Keywords:
Anemia;
Fetomaternal hemorrhage;
Exchange transfusion
- MeSH:
Anemia;
Anemia, Neonatal;
Blood Transfusion;
Chromatography;
Chromatography, High Pressure Liquid;
Female;
Fetal Blood;
Fetomaternal Transfusion;
Flow Cytometry;
Heart Failure;
Hemorrhage;
Humans;
Infant, Newborn;
Pregnancy;
Shock
- From:Korean Journal of Perinatology
2008;19(2):203-208
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Massive fetomaternal hemorrhage is major cause of neonatal anemia. And neonatal anemia is fatal disease of high mortality rate. Massive fetomaternal hemorrhage is defined as hemorrhage of fetal blood above 150 mL in the maternal circulation. Massive fetomaternal hemorrhage is infrequent but represents a fatal cause of perinatal death. To identify fetal blood in the maternal circulation, Kleihauer-Betke test or flow cytometry has been usually used. But recently HPLC (high performance liquid chromatography) is used in the detection and quantification of fetomaternal transfusion. In fetomaternal transfusion, anemic newborn must be treated when circulatory failure is present. Circulatory failure often necessitates blood transfusion. We report two cases of severe anemia due to massive fetomaternal hemorrhage in full term baby. Each case was diagnosed by high performance lipuid chromatography and treated with exchange transfusion in order to avoid fluid overload and subsequent heart failure.
