Histopathological Study of Erythema Mutiforma.
- Author:
Nak Joon CHO
- Publication Type:Original Article
- MeSH:
Biopsy;
Blister;
Dronabinol;
Edema;
Eosinophils;
Erythema Multiforme;
Erythema*;
Female;
Humans;
Iris;
Male;
Necrosis;
Seasons;
Skin
- From:Korean Journal of Dermatology
1979;17(1):65-71
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
55 patients which were clinically erythema multiforme and were diagnosed by punch biopsy, were studied clinically and histologically. The results obtained were as follows; l. Erythema multiforme was more common in female than in male and they were most frequently occured in 3rd decade. 2. In most patients individuaIs had various type of skin lesions (macule, papuIe, bullous and iris) and the skin lesions were scattered on the various sites of thc body. 3. 30 patients out of 55 patients had seasonal variation, especially frequently occured in spring k autumn. 4. In the histopathological study while dermal disturbance was a predominant finding in the macular lesion, epidermal necrosis was seen high frequency in bullous & iris lesions, 5. The papillary edema showed in most cases, however 2 cases out of 55 lesions had not papillary edema. 6. The dermal inflammatory infiltrates were composed chiefly of lyrnpho-histiocytic and significant number of eosinophils were present in the inflammatory infiltrate in 27 % of the bullous lesions.
