Peripapillary and Macular Microvasculature of the Retina in Primary Angle Closure Suspect
10.3341/jkos.2025.66.1.45
- Author:
Ui Seo PARK
1
;
Jung Lim KIM
Author Information
1. Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
- Publication Type:Original Article
- From:Journal of the Korean Ophthalmological Society
2025;66(1):45-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Purpose:To compare the macular and peripapillary vascular parameters between the primary angle closure suspect (PACS) eyes and normal control eyes using optical coherence tomography angiography (OCTA).
Methods:In this retrospective study, 42 PACS subjects and 38 normal individuals are included. Vessel density (VD) and perfusion density (PD) of the macular area and peripapillary area, and fovea avascular zone parameter were analyzed using OCTA and compared between two groups after adjustment for the axial length.
Results:There were no statistically significant differences in sex ratio, age, refractive errors and intraocular pressures between both groups. In the peripapillary area, inferior VD and PD in the outer zone were significantly lower in the PACS eyes, while the retinal nerve fiber layer thicknesses were similar between groups (p = 0.032, 0.026). In the macular superficial capillary plexus, inferior VD and PD in the inner zone, inferior VD and PD, nasal VD and PD in the outer zone were significantly lower in the PACS eyes, whereas ganglion cell inner plexiform layer thickness were similar between both groups (all p < 0.005).
Conclusions:The VDs and PDs of retinal capillaries in PACS eyes, which have no glaucomatous changes in the retinal nerve fiber layer and optic nerve disc, were significantly lower compared to normal eyes.
