Cancer-field surgery for endometrial cancer by robotic peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL)
- Author:
Paul BUDERATH
1
;
Tra My DANG
;
Rainer KIMMIG
Author Information
- Publication Type:Original Article
- From:Journal of Gynecologic Oncology 2025;36(1):e13-
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objective:Cancer-field surgery by peritoneal mesometrial resection and targeted compartmental lymphadenectomy (PMMR+TCL) for the treatment of endometrial cancer (EC) aims at optimal locoregional tumor control without the need for adjuvant radiotherapy.In a previous publication we could demonstrate the feasibility of the method and presented encouraging first oncologic data.
Methods:Following up our 2021 publication, we present data on the treatment of EC by PMMR+TCL in much larger cohort and with longer follow-up.
Results:One hundred and thirty-five patients with EC International Federation of Gynecology and Obstetrics (FIGO) I–IV (75.6% FIGO I) underwent cancer field surgery via PMMR+TCL for EC in the years 2016–2023. Mean follow-up in our cohort was 27.5 months (0, 83; 19.7). The procedure was feasible and safe with favorable intra-and postoperative complication rates. Even though 50.4% of patients had an indication for postoperative radiotherapy following national and international guidelines, the rate of postoperative irradiation administered was 10.4%. The overall recurrence rate was 8.1% and we observed 2 (1.5%) isolated locoregional recurrences.
Conclusion:Our results confirm the feasibility and safety of PMMR+TCL in EC patients.Oncologic data are very encouraging and hint at a superior locoregional control without adjuvant irradiation. Larger studies with longer follow-up will be needed to confirm these results.
