Bactericidal Effect of Disinfectant Tego-51(R).
- Author:
Jong Sung SUK
;
Hae Shim CHOI
;
Eui Chong KIM
- Publication Type:Original Article
- Keywords:
Disinfection;
Tego-51(R);
Amphoteric sunfactant;
Hospital infection
- MeSH:
Agar;
Bacillus subtilis;
Bacteria;
Cross Infection;
Disinfection;
Glucose;
Helicobacter;
Mirabilis;
Proteus mirabilis;
Sheep;
Skin;
Surface-Active Agents;
Yeasts
- From:Korean Journal of Nosocomial Infection Control
1997;2(1):55-59
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Disinfection is essential for the prevention of hospital infoction. Tego-51, one of the amphoteric surfactants based on the dodecyl-di( aminoethyl)-glycine, has been considered as an effctive disinfectant having a broad specturn of antimicrobial activity. We evaluated the disinfective activity of Tego-51 against several clinical isolates of bacteria and yeasts including Helicobacter pyiori. METHODS: Twenty three strains of vacteria including H. pylori, and a strain of yeast were exposed to the various concentrations (0.05%, 0.01%, 0.005%) of Tego-51 for the various periods (0.5, 1, 2, 4, 8, 16min). After the exposure to Tego-51 disinfectant, 0.01 mL of mixture of microorfanisms and Tego-51 was inoculated into brain-heart infusion broth, into Sabouraud dextrose agar. or Wilkins-Chalgren agar with 10% sheep blood, and incubated at 37 degrees C for 48 hours or in the Campy Pouch microaerophilic system. RESULTS: Most strains were killed within 30 seconds after an exposure to 0.01% of Tego-51, but Proteus mirabilis was eradicated after two minutes of exposure. At the concentration of 0.005 % concentration. P. mirabilis and Bacillus subtilis were killed after eight minutes od exposure. H. pylori was killed with 0.005% Tego-51within 30 seconds. Conslusions: This study showed that Tego-51disinfectant was effective for the disinfection of commonly isolated bacteria and yeast from hospital. It may be recommended that Tego-51 should be used at concentration greater than 0.1% for the effective disinfection of skin, instruments and hospital floors.
