Coronary Calcification Is Reversely Related with Bone and Hair Calcium: The Relationship among Different Calcium Pools in Body.
10.11005/jbm.2016.23.4.191
- Author:
Sang Hoon LEE
1
;
Soo Jung PARK
;
Kyu Nam KIM
;
Doo Yeoun CHO
;
Young Sang KIM
;
Bom Taeck KIM
Author Information
1. Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon, Korea. lovesong@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Bone density;
Calcium;
Hair;
Homeostasis;
Minerals;
Vascular calcification
- MeSH:
Absorptiometry, Photon;
Aging;
Blood Vessels;
Bone Density;
Calcium*;
Coronary Vessels;
Female;
Femur;
Femur Neck;
Hair*;
Homeostasis;
Humans;
Lumbar Vertebrae;
Minerals;
Miners;
Multidetector Computed Tomography;
Osteoporosis;
Retrospective Studies;
Spine;
Vascular Calcification
- From:Journal of Bone Metabolism
2016;23(4):191-197
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: With aging, calcium efflux from bone is increased with age-related bone loss, and it can reduce bone mineral density (BMD). On the contrary, age-related calcium adoption into arterial wall progressively stiffens blood vessels. Theses process insinuates shift of calcium among different pools in body. However, their relationships have not been elucidated yet. So we investigated the correlation among calcium contents in different body pools, such as hair, bone, and blood vessels in women. METHODS: We analyzed 50 females retrospectively who measured Agatston coronary artery calcium score (CACS), BMD, and hair calcium concentration at a regular health check-up in a university hospital. CACS was achieved by coronary multidetector computed tomography, BMD was measured by dual energy X-ray absorptiometry in the lumbar spine and femur, and hair calcium level was checked by hair tissue mineral analysis. RESULTS: CACS inversely correlated with BMD (r=-0.280, P=0.049 with lumbar vertebrae 1-4, r=-0.310, P=0.028 with femur neck, r=-0.333, P=0.018 with femur total) and hair calcium concentration (r=-0.352, P=0.012). CONCLUSIONS: CACS has negative correlation with BMD and hair calcium level in women. Different body calcium pools such as bone, hair and blood vessel significantly correlated each other.
