Clinical, EEG and MRI Findings in Newly Referred Seizure Patients.
- Author:
Ok Jun KIM
1
;
Su Chul PARK
;
Byung In LEE
;
Dong Ik KIM
Author Information
1. Department of Neurology, Yonsei University College of Medicine, Korea.
- Publication Type:Original Article
- MeSH:
Atrophy;
Electroencephalography*;
Encephalomalacia;
Epilepsy;
Granuloma;
Humans;
Magnetic Resonance Imaging*;
Pathology;
Seizures*;
Seizures, Febrile;
Temporal Lobe;
Vascular Malformations
- From:Journal of the Korean Neurological Association
1994;12(1):30-40
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinical, EEG and MRI assessments were conducted in 320 consecutive seizure patients referred to the Yonsei Epilepsy Clinic from october 1, 1991 to Feburary 28. 1993 Clinical assessment suggested that 91.9% of our patients had partial seizures and only 3.1% had generalized seizures. Among partial seizures. Temporal lobe seizure uas considered in 37.5%, localization undetermined partial seizure in 29.7%, extratemporal lobe seizure in 24.7%. Correlation with EEG findings in these patients showed disconcordance rate of 34.6% in generalized seizure, 29.1% in extratemporal lobe seizure, 15.8% in temporal lobe seizure, 5.3% in localization undetermined partial seizure. Structural lesions in MRI were found in 51.6% with hippocampal atrophy being the most frequently round(59.4%). Focal encephalomalacia comprised 15.8%, focal atrophy in 4.8*/o. vascular malformation in 4.2%, granuloma in 3.7%, tumor in 3.7%, cyst in 2.4%. Patients with clinically judged temporal lobe seizure had the most common structural lesions in MRI. Which were seen in 59.2%. Extratemporal lobe seizure had focal lesion in 50.6%. Localization undetermined partial seizure in 50.5%, and generalized seizure in 23.1%. Among 98 patients with hippocampal atrophy, 27 patients(27.6%) had dual pathology with focal encephalomalacia being the most common. 11 patients(11.3%) were suspected to have bilateral hippocampal atrophy. Hippocampal atrophy was more commonly seen in patients with history of febrile convulsion and in patients with severe seizure.
